Jackson: Lethal Amounts of Propofol in System

Jackson: Lethal Amounts of Propofol in System

Toxicology results finally showed that Michael Jackson had lethal amounts of the drug propofol in his system when he died. Los Angeles coroner Dr. Lakshmanan Sathyavagiswaran reached that preliminary conclusion after reviewing toxicology results carried out on Jackson’s blood, according to an affidavit.

Propofol, also known by its brand name Diprivan, is administered intravenously in operating rooms as a general anesthetic, the manufacturer AstraZeneca told CNN. A source close to the investigation told CNN that Dr. Conrad Murray is believed to have administered the drug to Jackson within 24 hours of his death on June 25.

The drug works as a depressant on the central nervous system. "It works on your brain," said Dr. Zeev Kain, the chair of the anesthesiology department at the University of California, Irvine. "It basically puts the entire brain to sleep."

However, once the infusion is stopped, the patient wakes up almost immediately. "So if you’re going to do this, you’d have to have somebody right there giving you the medication and monitoring you continuously," Kain said.

Dr. Hector Vila, chairman of the Ambulatory Surgery Committee for the American Society of Anesthesiologists, said he administers the drug during office procedures such as urology, dentistry, and gynecology. He also said it is the most common anesthetic for colonoscopies.

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